Prof. Carmit Levy

SCIENTIFIC PUBLICATIONS _ Carmit Levy

1. Levy C, Nechushtan H, Razin E. A new role for the STAT3 inhibitor, PIAS3: a repressor of microphthalmia transcription factor. J Biol Chem. 2002 Jan 18;277(3):1962-6. doi: 10.1074/jbc.M109236200. Epub 2001 Nov 14. PMID: 11709556.

2. Levy C, Sonnenblick A, Razin E. Role played by microphthalmia transcription factor phosphorylation and its Zip domain in its transcriptional inhibition by PIAS3. Mol Cell Biol. 2003 Dec;23(24):9073-80. doi: 10.1128/MCB.23.24.9073-9080.2003. PMID: 14645519; PMCID: PMC309632.

3. Sonnenblick A, Levy C, Razin E. Interplay between MITF, PIAS3, and STAT3 in mast cells and melanocytes. Mol Cell Biol. 2004 Dec;24(24):10584-92. doi: 10.1128/MCB.24.24.10584-10592.2004. PMID: 15572665; PMCID: PMC533964.

4. Miller AJ, Levy C, Davis IJ, Razin E, Fisher DE. Sumoylation of MITF and its related family members TFE3 and TFEB. J Biol Chem. 2005 Jan 7;280(1):146-55. doi: 10.1074/jbc.M411757200. Epub 2004 Oct 25. PMID: 15507434.

5. Sonnenblick A, Levy C, Razin E. Immunological trigger of mast cells by monomeric IgE: effect on microphthalmia transcription factor, STAT3 network of interactions. J Immunol. 2005 Aug 1;175(3):1450-5. doi: 10.4049/jimmunol.175.3.1450. PMID: 16034081.

6. Levy C, Lee YN, Nechushtan H, Schueler-Furman O, Sonnenblick A, Hacohen S, Razin E. Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3. Blood. 2006 Apr 1;107(7):2839-45. doi: 10.1182/blood-2005-08-3325. Epub 2005 Dec 20. PMID: 16368885.

7. Yokoyama S, Feige E, Poling LL, Levy C, Widlund HR, Khaled M, Kung AL, Fisher DE. Pharmacologic suppression of MITF expression via HDAC inhibitors in the melanocyte lineage. Pigment Cell Melanoma Res. 2008 Aug;21(4):457-63. doi: 10.1111/j.1755-148X.2008.00480.x. Epub 2008 Jun 27. PMID: 18627530; PMCID: PMC3771662.

8. Levy C, Khaled M, Iliopoulos D, Janas MM, Schubert S, Pinner S, Chen PH, Li S, Fletcher AL, Yokoyama S, Scott KL, Garraway LA, Song JS, Granter SR, Turley SJ, Fisher DE, Novina CD. Intronic miR-211 assumes the tumor suppressive function of its host gene in melanoma. Mol Cell. 2010 Dec 10;40(5):841-9. doi: 10.1016/j.molcel.2010.11.020. Epub 2010 Nov 25. PMID: 21109473; PMCID: PMC3004467. Ranked 8^th on the “must read” F1000 list, February 2011 and covered in News and Views of PCMR by Poenitzsch et al. April 2011.

9. Khaled M, Levy C, Fisher DE. Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit. Genes Dev. 2010 Oct 15;24(20):2276-81. doi: 10.1101/gad.1937710. PMID: 20952536; PMCID: PMC2956206. Covered in News and Views of PCMR by Ohanna M. et al. Nov 2010.

10. Levy C, Khaled M, Robinson KC, Veguilla RA, Chen PH, Yokoyama S, Makino E, Lu J, Larue L, Beermann F, Chin L, Bosenberg M, Song JS, Fisher DE. Lineage-specific transcriptional regulation of DICER by MITF in melanocytes. Cell. 2010 Jun 11;141(6):994-1005. doi: 10.1016/j.cell.2010.05.004. PMID: 20550935; PMCID: PMC2897150. Covered in News and Views of PCMR by Goding CR. Aug 2010.

11. Golan D, Levy C, Friedman B, Shomron N. Biased hosting of intronic microRNA genes. Bioinformatics. 2010 Apr 15;26(8):992-5. doi: 10.1093/bioinformatics/btq077. Epub 2010 Feb 24. PMID: 20185406.

12. Feige E, Yokoyama S, Levy C, Khaled M, Igras V, Lin RJ, Lee S, Widlund HR, Granter SR, Kung AL, Fisher DE. Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):E924-33. doi: 10.1073/pnas.1106351108. Epub 2011 Sep 26. PMID: 21949374; PMCID: PMC3203758.

13. Janas MM, Khaled M, Schubert S, Bernstein JG, Golan D, Veguilla RA, Fisher DE, Shomron N, Levy C*, Novina CD*. Feed-forward microprocessing and splicing activities at a microRNA-containing intron. PLoS Genet. 2011 Oct;7(10):e1002330. doi: 10.1371/journal.pgen.1002330. Epub 2011 Oct 20. PMID: 22028668; PMCID: PMC3197686. * indicates co-corresponding authors.

14. Tabach Y, Golan T, Hernández-Hernández A, Messer AR, Fukuda T, Kouznetsova A, Liu JG, Lilienthal I, Levy C*, Ruvkun G*. Human disease locus discovery and mapping to molecular pathways through phylogenetic profiling. Mol Syst Biol. 2013 Oct 1;9:692. doi: 10.1038/msb.2013.50. PMID: 24084807; PMCID: PMC3817400. * indicates co-corresponding authors.

15. Bell RE, Khaled M, Netanely D, Schubert S, Golan T, Buxbaum A, Janas MM, Postolsky B, Goldberg MS, Shamir R, Levy C. Transcription factor/microRNA axis blocks melanoma invasion program by miR-211 targeting NUAK1. J Invest Dermatol. 2014 Feb;134(2):441-451. doi: 10.1038/jid.2013.340. Epub 2013 Aug 9. PMID: 23934065.

16. Melamed Z, Levy A, Ashwal-Fluss R, Lev-Maor G, Mekahel K, Atias N, Gilad S, Sharan R, Levy C, Kadener S, Ast G. Alternative splicing regulates biogenesis of miRNAs located across exon-intron junctions. Mol Cell. 2013 Jun 27;50(6):869-81. doi: 10.1016/j.molcel.2013.05.007. Epub 2013 Jun 6. PMID: 23747012.

17. Shaham O, Gueta K, Mor E, Oren-Giladi P, Grinberg D, Xie Q, Cvekl A, Shomron N, Davis N, Keydar-Prizant M, Raviv S, Pasmanik-Chor M, Bell RE, Levy C, Avellino R, Banfi S, Conte I, Ashery-Padan R. Pax6 regulates gene expression in the vertebrate lens through miR-204. PLoS Genet. 2013;9(3):e1003357. doi: 10.1371/journal.pgen.1003357. Epub 2013 Mar 14. PMID: 23516376; PMCID: PMC3597499.

18. Edri R, Yaffe Y, Ziller MJ, Mutukula N, Volkman R, David E, Jacob-Hirsch J, Malcov H, Levy C, Rechavi G, Gat-Viks I, Meissner A, Elkabetz Y. Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors. Nat Commun. 2015 Mar 23;6:6500. doi: 10.1038/ncomms7500. PMID: 25799239; PMCID: PMC4383005.

19. Dror I, Golan T, Levy C, Rohs R, Mandel-Gutfreund Y. A widespread role of the motif environment in transcription factor binding across diverse protein families. Genome Res. 2015 Sep;25(9):1268-80. doi: 10.1101/gr.184671.114. Epub 2015 Jul 9. PMID: 26160164; PMCID: PMC4561487.

20. Golan T, Messer AR, Amitai-Lange A, Melamed Z, Ohana R, Bell RE, Kapitansky O, Lerman G, Greenberger S, Khaled M, Amar N, Albrengues J, Gaggioli C, Gonen P, Tabach Y, Sprinzak D, Shalom-Feuerstein R, Levy C. Interactions of Melanoma Cells with Distal Keratinocytes Trigger Metastasis via Notch Signaling Inhibition of MITF. Mol Cell. 2015 Aug 20;59(4):664-76. doi: 10.1016/j.molcel.2015.06.028. Epub 2015 Jul 30. PMID: 26236014. Covered in Cancer Discovery News: "Pinpointing Melanoma's Invasive Trigger", August 2015 and in Science Signaling News "Keratinocytes have the metastatic touch", September 2015.

21. Bell RE, Golan T, Sheinboim D, Malcov H, Amar D, Salamon A, Liron T, Gelfman S, Gabet Y, Shamir R, Levy C. Enhancer methylation dynamics contribute to cancer plasticity and patient mortality. Genome Res. 2016 May;26(5):601-11. doi: 10.1101/gr.197194.115. Epub 2016 Feb 23. PMID: 26907635; PMCID: PMC4864467. Covered in News and Views of PCMR "Switching enhancer methylation in metastatic melanoma”.

22. Levin L, Srour S, Gartner J, Kapitansky O, Qutob N, Dror S, Golan T, Dayan R, Brener R, Ziv T, Khaled M, Schueler-Furman O, Samuels Y, Levy C. Parkin Somatic Mutations Link Melanoma and Parkinson's Disease. J Genet Genomics. 2016 Jun 20;43(6):369-79. doi: 10.1016/j.jgg.2016.05.005. Epub 2016 May 13. PMID: 27297116.

23. Dror S, Sander L, Schwartz H, Sheinboim D, Barzilai A, Dishon Y, Apcher S, Golan T, Greenberger S, Barshack I, Malcov H, Zilberberg A, Levin L, Nessling M, Friedmann Y, Igras V, Barzilay O, Vaknine H, Brenner R, Zinger A, Schroeder A, Gonen P, Khaled M, Erez N, Hoheisel JD, Levy C. Melanoma miRNA trafficking controls tumour primary niche formation. Nat Cell Biol. 2016 Sep;18(9):1006-17. doi: 10.1038/ncb3399. Epub 2016 Aug 22. PMID: 27548915. Selected for Nature Cell Biology cover, September 2016, volume 18; covered in Nature Cell Biology News and Views: "Melanosomes foster tumour niche by activating CAFs", Susana García-Silva& Héctor Peinado; and highlighted in Nature reviews: "Melanoma melanosomes shape the stromal niche" David Killock.

24. Sheinboim D, Maza I, Dror I, Parikh S, Krupalnik V, Bell RE, Zviran A, Suita Y, Hakim O, Mandel-Gutfreund Y, Khaled M, Hanna JH, Levy C. OCT4 impedes cell fate redirection by the melanocyte lineage master regulator MITF in mouse ESCs. Nat Commun. 2017 Oct 18;8(1):1022. doi: 10.1038/s41467-017-01122-1. PMID: 29044103; PMCID: PMC5647326.

25. Brenner R, Ben-Zvi I, Shinar Y, Liphshitz I, Silverman B, Peled N, Levy C, Ben-Chetrit E, Livneh A, Kivity S. Familial Mediterranean Fever and Incidence of Cancer: An Analysis of 8,534 Israeli Patients With 258,803 Person-Years. Arthritis Rheumatol. 2018 Jan;70(1):127-133. doi: 10.1002/art.40344. Epub 2017 Dec 7. PMID: 28992365.

26. Amar D, Vizel A, Levy C, Shamir R. ADEPTUS: a discovery tool for disease prediction, enrichment and network analysis based on profiles from many diseases. Bioinformatics. 2018 Jun 1;34(11):1959-1961. doi: 10.1093/bioinformatics/bty027. PMID: 29360930.

27. Cohen-Tayar Y, Cohen H, Mitiagin Y, Abravanel Z, Levy C, Idelson M, Reubinoff B, Itzkovitz S, Raviv S, Kaestner KH, Blinder P, Elkon R, Ashery-Padan R. Pax6 regulation of Sox9 in the mouse retinal pigmented epithelium controls its timely differentiation and choroid vasculature development. Development. 2018 Aug 9;145(15):dev163691. doi: 10.1242/dev.163691. PMID: 29986868.

28.       Nordlinger A, Dror S, Elkahloun A, Del Rio J, Stubbs E, Golan T, Malcov H, Pricket TD, Cronin JC, Parikh S, Labes S, Thomas L, Yankovitz G, Tabach Y, Levy C, Samuels Y, Khaled M. Mutated MITF-E87R in Melanoma Enhances Tumor Progression via S100A4. J Invest Dermatol. 2018 Oct;138(10):2216-2223. doi: 10.1016/j.jid.2018.03.1524. Epub 2018 Apr 19. PMID: 29679610.

29.       Malcov-Brog H, Alpert A, Golan T, Parikh S, Nordlinger A, Netti F, Sheinboim D, Dror I, Thomas L, Cosson C, Gonen P, Stanevsky Y, Brenner R, Perluk T, Frand J, Elgavish S, Nevo Y, Rahat D, Tabach Y, Khaled M, Shen-Orr SS, Levy C. UV-Protection Timer Controls Linkage between Stress and Pigmentation Skin Protection Systems. Molecular Cell. 2018 Nov 1;72(3):444-456.e7. doi: 10.1016/j.molcel.2018.09.022. Epub 2018 Oct 25. PMID: 30401431; PMCID: PMC6224604. Selected for Molecular Cell cover, November 2018 and for Molecular Cell Early Press, October 2018.

30. Raz Y, Cohen N, Shani O, Bell RE, Novitskiy SV, Abramovitz L, Levy C, Milyavsky M, Leider-Trejo L, Moses HL, Grisaru D, Erez N. Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer. J Exp Med. 2018 Dec 3;215(12):3075-3093. doi: 10.1084/jem.20180818. Epub 2018 Nov 23. PMID: 30470719; PMCID: PMC6279405.

31. Brenner R, Kivity S, Peker M, Reinhorn D, Keinan-Boker L, Silverman B, Liphsitz I, Kolitz T, Levy C, Shlomi D, Pillar G, Peled N. Increased Risk for Cancer in Young Patients with Severe Obstructive Sleep Apnea. Respiration. 2019;97(1):15-23. doi: 10.1159/000486577. Epub 2018 Nov 12. PMID: 30419556.

32. Golan T, Levy C. Negative Regulatory Loop between Microphthalmia-Associated Transcription Factor (MITF) and Notch Signaling. Int J Mol Sci. 2019 Jan 29;20(3):576. doi: 10.3390/ijms20030576. PMID: 30699982; PMCID: PMC6387231.

33. Golan T, Parikh R, Jacob E, Vaknine H, Zemser-Werner V, Hershkovitz D, Malcov H, Leibou S, Reichman H, Sheinboim D, Percik R, Amar S, Brenner R, Greenberger S, Kung A, Khaled M, Levy C. Adipocytes sensitize melanoma cells to environmental TGF-β cues by repressing the expression of miR-211. Science Signaling. 2019 Jul 23;12(591):eaav6847. doi: 10.1126/scisignal.aav6847. PMID: 31337739. Selected for Science Signaling cover, July 2019.

34. Glaich O, Parikh S, Bell RE, Mekahel K, Donyo M, Leader Y, Shayevitch R, Sheinboim D, Yannai S, Hollander D, Melamed Z, Lev-Maor G, Ast G, Levy C. DNA methylation directs microRNA biogenesis in mammalian cells. Nature Communications. 2019 Dec 11;10(1):5657. doi: 10.1038/s41467-019-13527-1. PMID: 31827083; PMCID: PMC6906426.

35. Gilat N, Torchinsky D, Margalit S, Michaeli Y, Avraham S, Sharim H, Elkoshi N, Levy C, Zirkin S, Ebenstein Y. Rapid Quantification of Oxidation and UV Induced DNA Damage by Repair Assisted Damage Detection-(Rapid RADD). Anal Chem. 2020 Jul 21;92(14):9887-9894. doi: 10.1021/acs.analchem.0c01393. Epub 2020 Jul 8. PMID: 32578422.

36. Netanely D, Leibou S, Parikh R, Stern N, Vaknine H, Brenner R, Amar S, Factor RH, Perluk T, Frand J, Nizri E, Hershkovitz D, Zemser-Werner V, Levy C, Shamir R. Classification of node-positive melanomas into prognostic subgroups using keratin, immune, and melanogenesis expression patterns. Oncogene. 2021 Mar;40(10):1792-1805. doi: 10.1038/s41388-021-01665-0. Epub 2021 Feb 9. PMID: 33564068; PMCID: PMC7946641.

37. Sheinboim D, Parikh S, Parikh R, Menuchin A, Shapira G, Kapitansky O, Elkoshi N, Ruppo S, Shaham L, Golan T, Elgavish S, Nevo Y, Bell RE, Malcov H, Shomron N, Taub JW, Izraeli S, Levy C. Slow transcription of the 99a/let-7c/125b-2 cluster results in differential miRNA expression and promotes melanoma phenotypic plasticity. J Invest Dermatol. 2021 Jun 26:S0022-202X(21)01406-8. doi: 10.1016/j.jid.2021.03.036. Epub ahead of print. PMID: 34186058.

38. Ofir-Birin Y, Ben Ami Pilo H, Cruz Camacho A, Rudik A, Rivkin A, Revach OY, Nir N, Block Tamin T, Abou Karam P, Kiper E, Peleg Y, Nevo R, Solomon A, Havkin-Solomon T, Rojas A, Rotkopf R, Porat Z, Avni D, Schwartz E, Zillinger T, Hartmann G, Di Pizio A, Quashie NB, Dikstein R, Gerlic M, Torrecilhas AC, Levy C, Nolte-'t Hoen ENM, Bowie AG, Regev-Rudzki N. Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration. Nature Communications. 2021 Aug 11;12(1):4851. doi: 10.1038/s41467-021-24997-7. PMID: 34381047; PMCID: PMC8357946

39. Parikh R, Sorek E, Parikh S, Michael K, Bikovski L, Tshori S, Shefer G, Mingelgreen S, Zornitzki T, Knobler H, Chodick G, Mardamshina M, Boonman A, Kronfeld-Schor N, Bar-Joseph H, Ben-Yosef D, Amir H, Pavlovsky M, Matz H, Ben-Dov T, Golan T, Nizri E, Liber D, Liel Y, Brenner R, Gepner Y, Karnieli-Miller O, Hemi R, Shalgi R, Kimchi T, Percik R, Weller A, Levy C. Skin exposure to UVB light induces a skin-brain-gonad axis and sexual behavior. Cell Reports. 2021 Aug 24;36(8):109579. doi: 10.1016/j.celrep.2021.109579. PMID: 34433056; PMCID: PMC8411113. Selected for Cell Reports cover, August 2021.

40. Agbarya A, Sarel I, Ziv-Baran T, Agranat S, Schwartz O, Shai A, Nordheimer S, Fenig S, Shechtman Y, Kozlener E, Taha T, Nasrallah H, Parikh R, Elkoshi N, Levy C, Khoury R, Brenner R. Efficacy of the mRNA-Based BNT162b2 COVID-19 Vaccine in Patients with Solid Malignancies Treated with Anti-Neoplastic Drugs. Cancers (Basel). 2021 Aug 20;13(16):4191. doi: 10.3390/cancers13164191. PMID: 34439346; PMCID: PMC8391288.

41. Parikh S, Parikh R, Michael K, Bikovski L, Barnabas G, Mardamshina M, Hemi R, Manich P, Goldstein N, Malcov-Brog H, Ben-Dov T, Glaich O, Liber D, Bornstein Y, Goltseker K, Ben-Bezalel R, Pavlovsky M, Golan T, Spitzer L, Matz H, Gonen P, Percik R, Leibou L, Perluk T, Ast G, Frand J, Brenner R, Ziv T, Khaled M, Ben-Eliyahu S, Barak S, Karnieli-Miller O, Levin E, Gepner Y, Weiss R, Pfluger P, Weller A, Levy C. Food-seeking behavior is triggered by skin ultraviolet exposure in males. Nature Metabolism. 2022 Jul;4(7):883-900. doi: 10.1038/s42255-022-00587-9. Epub 2022 Jul 11. PMID: 35817855; PMCID: PMC9314261..

42. Sheinboim D, Parikh S, Manich P, Markus I, Dahan S, Parikh R, Stubbs E, Cohen G, Zemser-Werner V, Bell RE, Ruiz SA, Percik R, Brenner R, Leibou S, Vaknine H, Arad G, Gerber Y, Keinan-Boker L, Shimony T, Bikovski L, Goldstein N, Constantini K, Labes S, Mordechai S, Doron H, Lonescu A, Ziv T, Nizri E, Choshen G, Eldar-Finkelman H, Tabach Y, Helman A, Ben-Eliyahu S, Erez N, Perlson E, Geiger T, Ben-Zvi D, Khaled M, Gepner Y, Levy C. An Exercise-Induced Metabolic Shield in Distant Organs Blocks Cancer Progression and Metastatic Dissemination. Cancer Research. 2022 Nov 15;82(22):4164-4178. doi: 10.1158/0008-5472.CAN-22-0237. PMID: 36084256. Selected for Cancer Research cover, November 2022.

43. Gutwillig, A., Santana-Magal, N., Farhat-Younis, L., Rasoulouniriana, D., Madi, A., Luxenburg, C., Cohen, J., Padmanabhan, K., Shomron, N., Shapira, G. and Gleiberman, A., Parikh, R., Levy, C., Feinmesser, M., Hershkovitz, D., Zemser-Werner, V., Zlotnik, O., Kroon, S., Hardt, WD., Debets, R., Reticker-Flynn, NE., Rider, P. and Carmi, Y. Transient cell-in-cell formation underlies tumor relapse and resistance to immunotherapy. 2022 Dec. eLife 11:e80315 doi.org/10.7554/eLife.80315

44. Maliah, A., Parikh, R., Tayer-Shifman, O.E., Kimhi, O., Gepstein, R., Halperin, T., Levy, Y., Levy, C., Basson, Y.P.P. and Kivity, S. Steroid treatment suppresses the CD4+ T-cell response to the third dose of mRNA COVID-19 vaccine in systemic autoimmune rheumatic disease patients.2022. Scientific Reports, 12(1), p.21056. doi.org/10.1038/s41598-022-25642-z

45. Zornitzki, T., Tshori, S., Shefer, G., Mingelgrin, S., Levy, C., & Knobler, H. (2022). Seasonal Variation of Testosterone Levels in a Large Cohort of Men. International Journal of Endocrinology, 2022. doi.org/10.1155/2022/6093092

46. Sarfstein, R., Nagaraj, K., Parikh, S., Levy, C., Laron, Z., Benayahu, D., & Werner, H. 2022. Identification of UDP-Glucuronosyltransferase 2B15 (UGT2B15) as a Target for IGF1 and Insulin Action. Cells 2022, 11, 1627.

47. Leichner GS, Schweitzer I, Dror S, Levin L, Geva P, Golan T, Zaremba L, Shapira G, Parikh R, Shomron N, Barzilai A, Hoheisel JD, Levy C, Greenberger S. Primary Melanoma miRNA Trafficking Induces Lymphangiogenesis. J Invest Dermatol. 2023 Sep;143(9):1788-1798.e7. doi: 10.1016/j.jid.2023.02.030. Epub 2023 Mar 17. PMID: 36934839.

48. Elkoshi N, Parikh S, Malcov-Brog H, Parikh R, Manich P, Netti F, Maliah A, Elkoshi H, Haj M, Rippin I, Frand J, Perluk T, Haiat-Factor R, Golan T, Regev-Rudzki N, Kiper E, Brenner R, Gonen P, Dror I, Levi H, Hameiri O, Cohen-Gulkar M, Eldar-Finkelman H, Ast G, Nizri E, Ziv Y, Elkon R, Khaled M, Ebenstein Y, Shiloh Y, Levy C. Ataxia Telangiectasia Mutated Signaling Delays Skin Pigmentation upon UV Exposure by Mediating MITF Function toward DNA Repair Mode. J Invest Dermatol. 2023 Dec;143(12):2494-2506.e4. doi: 10.1016/j.jid.2023.03.1686. Epub 2023 May 25. PMID: 37236596.

49. Parikh S, Parikh R, Harari M, Weller A, Bikovski L, Levy C. Skin epidermal keratinocyte p53 induces food uptake upon UV exposure. Front Behav Neurosci. 2023 Dec 12;17:1281274. doi: 10.3389/fnbeh.2023.1281274. eCollection 2023.

50. Parikh R, Parikh S, Hemi R, Elkoshi N, Gepner Y, Levy C, Percik R. Seasonal AMH variability implies a positive effect of UV exposure on the deterioration of ovarian follicles. Steroids. 2023 Dec;200:109307. doi: 10.1016/j.steroids.2023.109307. Epub 2023 Aug 28.

51. Parikh R, Parikh S, Berzin D, Vaknine H, Ovadia S, Likonen D, Greenberger S, Scope A, Elgavish S, Nevo Y, Plaschkes I, Nizri E, Kobiler O, Maliah A, Zaremba L, Mohan V, Sagi I, Ashery-Padan R, Carmi Y, Luxenburg C, Hoheisel JD, Khaled M, Levesque MP, Levy C. Recycled melanoma-secreted melanosomes regulate tumor-associated macrophage diversification. EMBO J. 2024 May 8. doi: 10.1038/s44318-024-00103-7. Epub ahead of print. PMID: 38719996.

52. Maliah A, Santana-Magal N, Parikh S, Gordon S, Reshef K, Sade Y, Khateeb A, Richter A, Gutwillig A, Parikh R, Golan T, Krissi M, Na M, Binshtok G, Manich P, Elkoshi N, Grisaru-Tal S, Zemser-Werner V, Brenner R, Vaknine H, Nizri E, Moyal L, Amitay-Laish I, Rosemberg L, Munitz A, Kronfeld-Schor N, Shifrut E, Kobiler O, Madi A, Geiger T, Carmi Y, Levy C. Crosslinking of Ly6a metabolically reprograms CD8 T cells for cancer immunotherapy. Nature Communications 2024 Sep 27;15(1):8354. doi: 10.1038/s41467-024-52079-x. PMID: 39333093; PMCID: PMC11437002.

53. Bertrand JU, Petit V, Aktary Z, de la Grange P, Elkoshi N, Sohier P, Delmas V, Levy C, Larue L. Loss of Dicer in Newborn Melanocytes Leads to Premature Hair Graying and Changes in Integrin Expression. J Invest Dermatol. 2024 Mar;144(3):601-611. doi: 10.1016/j.jid.2023.08.023. Epub 2023 Sep 20. PMID: 37739336.

54. Beitner A, Abu-Abeid A, Dayan D, Gat A, Miodovnik M, Levy C, Nizri E. (2025). Patterns of expression and prognostic implication of glycoprotein nonmetastatic protein B (GPNMB) expression in sentinel lymph nodes of melanoma patients. Melanoma Res. 2025 Jun 1;35(3):155-161. doi: 10.1097/CMR.0000000000001019. Epub 2025 Apr 29. PMID: 39951029.

55. Afratis NA, Parikh S, Adir I, Parikh R, Solomonov I, Kollet O, Gelb S, Sade Y, Vaknine H, Zemser-Werner V, Brener R, Nizri E, Hershkovitz D, Ricard-Blum S, Levy C#, Sagi I#. (2025). Biselective remodeling of the melanoma tumor microenvironment prevents metastasis and enhances immune activation in mouse models. Science Translational Medicine. 2025 Oct 15;17(820):eadp3236. doi: 10.1126/scitranslmed.adp3236. Epub 2025 Oct 15. PMID: 41091916.

56. Haj M, Frey Y, Levon A, Maliah A, Ben-Yishay T, Slutsky R, Smoom R, Tzfati Y, Ben-David U, Levy C, Elkon R, Ziv Y, Shiloh Y. (2025). The cGAS-STING, p38 MAPK, and p53 pathways link genome instability to accelerated cellular senescence in ATM-deficient murine lung fibroblasts. Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2419196122. doi: 10.1073/pnas.2419196122. Epub 2025 Jan 7. PMID: 39772747; PMCID: PMC11745328.

57. Chemla Y, Itzhaki O, Melamed S, Weller C, Sade Y, Manich P, Reshef K, Xenidis N, Maliah A, Levy G, Parikh R, Bartok O, Levy O, Tal I, Aziel G, Nissani A, Yunger S, Likonen D, Kliminsky V, Golan T, Capron C, Ace V, Levy R, Rasoulouniriana D, Eyal Z, Barzilay Y, Balaban R, Khateeb A, Khosravi R, Grau A, Ziv T, Greenberg P, Netanely D, Vaknin H, Wu X, Amitay Y, Brenner R, Martínez Gómez JM, Hershkovitz D, Yardeni T, Zemser-Werner V, Kobiler O, Friedmann Y, Bassan D, Shamir R, Eisenbach L, Santana-Magal N, Milyavsky M, Eisenberg G, Keren L, Cohen M, Gur D, Barak B, Lotem M, Sprinzak D, Greenberger S, Fisher D, Besser MJ, Khaled M, Close P, Shapira R, Apcher S, Madi A, Levesque MP, Rapino F, Carmi Y, Parikh S, Samuels Y, Levy C. (2026). HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion. Cell. 2026 Jan 8:S0092-8674(25)01316-9. doi: 10.1016/j.cell.2025.11.020. Epub ahead of print. PMID: 41401806.

58. Maliah A, Parikh S, Stevenson AC, Bijaoui D, Goodman E, Sade Y, Parikh R, Binshtok G, Manich P, Golan T, Tal I, Weller R, Virós A, Percik R, Granot Z, Luxenburg C, Carmi Y, Khaled M, Dibben C, Levy C. (2026). UV-induced immune modulation in the lung niche slows cancer progression. Scientific Reports. In press.

REVIEWS

1. Levy C, Khaled M, Fisher DE. MITF: master regulator of melanocyte development and melanoma oncogene. Trends Mol Med. 2006 Sep;12(9):406-14. doi: 10.1016/j.molmed.2006.07.008. Epub 2006 Aug 8. PMID: 16899407.

2. Shomron N, Levy C. MicroRNA-biogenesis and Pre-mRNA splicing crosstalk. J Biomed Biotechnol. 2009;2009:594678. doi: 10.1155/2009/594678. Epub 2009 Jul 6. PMID: 19606257; PMCID: PMC2709726.

3. Levy C, Fisher DE. Dual roles of lineage restricted transcription factors: the case of MITF in melanocytes. Transcription. 2011 Jan-Feb;2(1):19-22. doi: 10.4161/trns.2.1.13650. PMID: 21326905; PMCID: PMC3023642.

4. Bell RE, Levy C. The three M's: melanoma, microphthalmia-associated transcription factor and microRNA. Pigment Cell Melanoma Res. 2011 Dec;24(6):1088-106. doi: 10.1111/j.1755-148X.2011.00931.x. PMID: 22004179.

5. Levy C, Khaled M. Ecad vitiliGONE. Pigment Cell Melanoma Res. 2015 Jul;28(4):376-7. doi: 10.1111/pcmr.12377. PMID: 25864372.

6. Levy C, Golan T, Fisher DE. miRNA-211 stops the clock. Noncoding RNA Investig. 2018 May;2:25. doi: 10.21037/ncri.2018.04.05. Epub 2018 May 6. PMID: 30198016; PMCID: PMC6124680.

7. Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Burd CE, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, Leucci E, Levy C, Lombard DB, Lund AW, Marie KL, Marine JC, Marais R, McMahon M, Robles-Espinoza CD, Ronai ZA, Samuels Y, Soengas MS, Villanueva J, Weeraratna AT, White RM, Yeh I, Zhu J, Zon LI, Hurlbert MS, Merlino G. Melanoma models for the next generation of therapies. Cancer Cell. 2021 May 10;39(5):610-631. doi: 10.1016/j.ccell.2021.01.011. Epub 2021 Feb 4. PMID: 33545064; PMCID: PMC8378471.

8. Parikh S, Levy C. The Hungry Side of Skin. (2024). J Invest Dermatol. 2024 Oct;144(10):2117-2119. doi: 10.1016/j.jid.2024.04.030. Epub 2024 Aug 30. PMID: 39217538.