Prof. Ayelet Lesman

Dr. Ayelet Lesman's research is at the interface between mechanics and biology. Her laboratory investigates the effect of mechanical forces on biological processes such as cell migration, organization and communication between cells. Particular emphasis is on the interaction of cells with nonlinear fibrous environments that mimic tissue conditions and on long-range mechanical interaction between cells mediated by fibrous environments.

Dr. Ayelet Lesman has acquired her education at the Technion where she earned her BSc in Materials Engineering and Chemistry, and her MSc and PhD in Biomedical Engineering. She conducted her post-doctoral research at the California Institute of Technology (Cal Tech) at the Faculty of Chemical Engineering in cooperation with Mechanical Engineering.

After a period of post-doctoral work at the Weizmann Institute in the Faculty of Biology, Dr. Lesman joined Tel Aviv University's School of Mechanical Engineering as a Senior Lecturer.

Ran S Sopher, Hanan Tokash, Sari Natan, Mirit Sharabi, Ortal Shelah, Oren Tchaicheeyan, Ayelet Lesman. Nonlinear elasticity of the ECM fibers facilitates efficient inter-cellular communication. Biophysical J. 2;115(7), 2018

Shahar Goren, Yoni Koren, Xinpeng Xu, Ayelet Lesman. Elastic Anisotropy Governs the Range of Cell-Induced Displacements. Biophysical Journal. March 2020 .Volume 118, Issue 5, March 2020.

Sari Natan, Yoni Koren, Ortal Shelah, Shahar Goren, Ayelet Lesman. Long-range mechanical coupling of cells in 3D fibrin gels. Molecular Biology of the Cell, Volume 31, No. 14, July 2020.

Avraham Kolel, Bar Ergaz, Shahar Goren, Oren Tchaicheeyan, Ayelet Lesman. Strain Gradient Programming in 3D Fibrous Hydrogels to Direct Graded Cell Alignment. Small Methods, Volume 7, Issue 1, Jan 2023.

Shahar Goren, Maayan Levin, Guy Brand, Ayelet Lesman, and Raya Sorkin. Probing Local Force Propagation in Tensed Fibrous Gels. Small, In-Press, Nov 2022.

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