Prof. Ohad Gal-Mor

2018:  Present Associate Professor. Department of Clinical Microbiology and Immunology, Faculty of Medical and Health Sciences, Tel-Aviv University

2014 – 2018:  Senior Lecturer (Assistant Professor). Department of Clinical Microbiology and Immunology, Faculty of Medical and Health Sciences, Tel-Aviv University 

2009 – Present:  Director. The Infectious Diseases Research Laboratory, Sheba Medical Center, Tel- Hashomer Israel.

2003 – 2008:  Postdoctoral Fellow. University of British Columbia, Michael Smith Laboratories, Vancouver, Canada. Mentor: Prof. Brett Finlay.

1998 – 2003:  Graduate Student (Direct-Track). Tel-Aviv University, the faculty of Life Sciences, Department of Molecular Microbiology and Biotechnology, Tel-Aviv, Israel.

1. Why and how distinct Salmonella serovars are differ in their host-specificity and clinical outcome.

2. Virulence regulation in Salmonella and its response to host and environmental signals.

3. Mechanisms of horizontal gene transfer in Salmonella and its effect on Salmonella evolution, epidemiology and virulence.

4. The biology of invasive and persistent Salmonella infections.

For full list of publications see https://pubmed.ncbi.nlm.nih.gov/?term=Gal-Mor%20O&sort=date

1. The transcriptional regulation of the horizontally acquired iron uptake system, yersiniabactin and its contribution to oxidative stress tolerance and pathogenicity of globally emerging salmonella strains.  Diamant I, Adani B, Sylman M, Rahav G, Gal-Mor O. Gut Microbes. 2024. 16(1):2369339. PMID: 3896296.

2. Persistent Salmonella infections in humans are associated with mutations in the BarA/SirA regulatory pathway. Grote A, Piscon B, Manson AL, Adani B, Cohen H, Livny J, Earl AM, Gal-Mor O. Cell Host Microbe. 2024. 10;32(1):79-92.e7. PMID: 38211565.

3. A new Salmonella enterica serovar that was isolated from a wild sparrow presents a distinct genetic, metabolic and virulence profile. Cohen E, Azriel S, Auster O, Gal A, Mikhlin S, Crauwels S, Rahav G, Gal-Mor O.  Microbes Infect. 2024. 26(3):105249. PMID: 37956735.

4. The Effect of Outer Space and Other Environmental Cues on Bacterial Conjugation. Piscon B, Pia Esposito E, Fichtman B, Samburski G, Efremushkin L, Amselem S, Harel A, Rahav G, Zarrilli R, Gal-Mor O. Microbiol Spectr. 2023. 11(3):e0368822. PMID: 36995224.

5. The emergence of a multidrug resistant Salmonella Muenchen in Israel is associated with horizontal acquisition of the epidemic pESI plasmid. Cohen E, Kriger O, Amit S, Davidovich M, Rahav G, Gal-Mor O. Clin Microbiol Infect. 2022. (11):1499.e7-1499.e14. PMID: 35654317.

6. Intracellular Salmonella Paratyphi A is motile and differs in the expression of flagella-chemotaxis, SPI-1 and carbon utilization pathways in comparison to intracellular S. Typhimurium. Cohen H, Hoede C, Scharte F, Coluzzi C, Cohen E, Shomer I, Mallet L, Holbert S, Serre RF, Schiex T, Virlogeux-Payant I, Grassl GA, Hensel M, Chiapello H, Gal-Mor O. PLoS Pathog. 2022. 18(4):e1010425. PMID: 35381053.

7. The ancestral stringent response potentiator, DksA has been adapted throughout Salmonella evolution to orchestrate the expression of metabolic, motility, and virulence pathways. Cohen H, Adani B, Cohen E, Piscon B, Azriel S, Desai P, Bähre H, McClelland M, Rahav G, Gal-Mor O. Gut Microbes. 2022. 14(1):1997294. PMID: 34923900.

8. Pathoadaptation of the passerine-associated Salmonella enterica serovar Typhimurium lineage to the avian host. Cohen E, Azriel S, Auster O, Gal A, Zitronblat C, Mikhlin S, Scharte F, Hensel M, Rahav G, Gal-Mor O.  PLoS Pathog. 2021. 17(3):e1009451. PMID: 33739988.

9. Genome Sequence of an Emerging Salmonella enterica Serovar Infantis and Genomic Comparison with Other S. Infantis Strains. Cohen E, Rahav G, Gal-Mor O. Genome Biol Evol. 2020. 12(3):151-159. PMID: 32145019.

10. Emergence of new variants of antibiotic resistance genomic islands among multidrug-resistant Salmonella enterica in poultry. Cohen E, Davidovich M, Rokney A, Valinsky L, Rahav G, Gal-Mor O. Environ Microbiol. 2020. 22(1):413-432. PMID: 31715658.

11. Differences in the expression of SPI-1 genes pathogenicity and epidemiology between the emerging Salmonella enterica serovar Infantis and the model Salmonella enterica serovar Typhimurium. Aviv G, Cornelius A, Davidovich M, Cohen H, Suwandi A, Galeev A, Steck N, Azriel S, Rokney A, Valinsky L, Rahav G, Grassl GA, Gal-Mor O. J Infect Dis. 2019. 220(6):1071-1081. PMID: 31062854.

12. Persistent Infection and Long-Term Carriage of Typhoidal and Nontyphoidal Salmonellae. Gal-Mor O. Clin Microbiol Rev. 2018. 32(1):e00088-18. PMID: 30487167.

13. The Typhi colonization factor (Tcf) is encoded by multiple non-typhoidal Salmonella serovars but exhibits a varying expression profile and interchanging contribution to intestinal colonization. Azriel S, Goren A, Shomer I, Aviv G, Rahav G, Gal-Mor O. Virulence. 2017. 8(8):1791-1807. PMID: 28922626.

14. The plasmid-encoded Ipf and Klf fimbriae display different expression and varying roles in the virulence of Salmonella enterica serovar Infantis in mouse vs. avian hosts. Aviv G, Elpers L, Mikhlin S, Cohen H, Vitman Zilber S, Grassl GA, Rahav G, Hensel M, Gal-Mor O. PLoS Pathog. 2017. 13(8):e1006559. PMID: 28817673.

15. Horizontal Transfer of the Salmonella enterica Serovar Infantis Resistance and Virulence Plasmid pESI to the Gut Microbiota of Warm-Blooded Hosts. Aviv G, Rahav G, Gal-Mor O. mBio. 2016. 7(5):e01395-16. PMID: 27601577.

16. Differences in Host Cell Invasion and Salmonella Pathogenicity Island 1 Expression between Salmonella enterica Serovar Paratyphi A and Nontyphoidal S. Typhimurium. Elhadad D, Desai P, Grassl GA, McClelland M, Rahav G, Gal-Mor O. Infect Immun. 2016. 84(4):1150-1165. PMID: 26857569.

17. Persistent Infections by Nontyphoidal Salmonella in Humans: Epidemiology and Genetics. Marzel A, Desai PT, Goren A, Schorr YI, Nissan I, Porwollik S, Valinsky L, McClelland M, Rahav G, Gal-Mor O. Clin Infect Dis. 2016. 62(7):879-886. PMID: 26740515.

18. The Stringent Response Regulator DksA Is Required for Salmonella enterica Serovar Typhimurium Growth in Minimal Medium, Motility, Biofilm Formation, and Intestinal Colonization. Azriel S, Goren A, Rahav G, Gal-Mor O. Infect Immun. 2015. 84(1):375-84. PMID: 26553464.

19. Feverlike Temperature is a Virulence Regulatory Cue Controlling the Motility and Host Cell Entry of Typhoidal Salmonella. Elhadad D, McClelland M, Rahav G, Gal-Mor O. J Infect Dis. 2015. 212(1):147-56. PMID: 25492917.

20. Same species, different diseases: how and why typhoidal and non-typhoidal Salmonella enterica serovars differ. Gal-Mor O, Boyle EC, Grassl GA. Front Microbiol. 2014. 5:391. PMID: 25136336.

21. A unique megaplasmid contributes to stress tolerance and pathogenicity of an emergent Salmonella enterica serovar Infantis strain. Aviv G, Tsyba K, Steck N, Salmon-Divon M, Cornelius A, Rahav G, Grassl GA, Gal-Mor O. Environ Microbiol. 2014. 16(4):977-94. PMID: 24320043.

22. Virulence gene profiling and pathogenicity characterization of non-typhoidal Salmonella accounted for invasive disease in humans. Suez J, Porwollik S, Dagan A, Marzel A, Schorr YI, Desai PT, Agmon V, McClelland M, Rahav G, Gal-Mor O. PLoS One. 2013. 8(3):e58449. PMID: 23505508.

22. Molecular and cellular characterization of a Salmonella enterica serovar Paratyphi A outbreak strain and the human immune response to infection. Gal-Mor O, Suez J, Elhadad D, Porwollik S, Leshem E, Valinsky L, McClelland M, Schwartz E, Rahav G. Clin Vaccine Immunol. 2012. 19(2):146-56. PMID: 22190395.